EFFECT OF ETHANOLIC LEAVES EXTRACT OF Piper nigrum & Piper betle ON MULTI-DRUG RESISTANT MICROORGANISMS THAT AFFECT THE DIABETIC PATIENTS
Authors: KAVITHA S , RAMESHKANNAN MV, MANI P

ABSTRACT
In Indian conventional medicine system, Piper nigrum and Piper betle are the commonly used medicinal plants for various therapeutic purposes such as treatment of antiulcer, antibacterial, antioxidant, anticancer etc., Diabetics mellitus is a disorder that occurs due to the improper functioning of pancreas in secreting insulin that leads to increase in blood glucose level which leads to various symptoms like frequent urination, loss of weight, obesity, damage to the cells, dizziness, low blood pressure and very frequent infection by pathogens such as Escherchia coli, Staphylococcus mutans, Klebseilla pneumonia, Bacillus subtilis , Pseudomonas aeruginosa and Candida albicans. In the present study aims to qualitative analysis the secondary metabolites from the ethanolic leaves extract of Piper nigrum and Piper betle and testing the ethanolic leaves extract against multidrug resistant microorganisms of diabetic foot ulcer. The results showed that the ethanolic leaves extract of Piper nigrum and Piper betle exhibited the effective antibacterial activity against the multidrug resistance organisms that affects the diabetic patients. Keywords: Piper nigrum, Piper betle, Antibacterial Activity, Ethanolic extract and Phytochemical analysis
Publication date: 01/01/2020
    https://ijbpas.com/pdf/2020/January/MS_IJBPAS_2019_4894.pdf
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https://doi.org/10.31032/IJBPAS/2020/9.1.4894