ABSTRACT

The present investigation was carried out with a focus to explore the biologically active phytoconstituents in Gmelina arborea Roxb. root, a widely exploited anti-inflammatory drug material used in most of the traditional, complementary and alternative medical (TCAM) systems. Gas chromatography coupled mass spectrometric (GC-MS) analyses was carried out in the ethanolic extract as part of the dereplication process. The active principles with their retention time, peak area and m/z value of the compounds were detected and the analyses revealed the presence of 23 phytocompounds which were subsequently identified through the interpretation of mass spectra and comparison ofthe chromatogram retention values with the entries in NIST 11 and WILEY 8 databases. Keywords: Gmelina arborea, Root, GC-MS analyses, Dereplication, Anti-inflammatory drug
Publication date: 01/04/21

https://www.ijbpas.com/pdf/2021/April/MS_IJBPAS_2021_5614.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.4.5614