ETIOLOGY, PATHOPHYSIOLOGY AND MEDICAL MANAGEMENT OF GASTROESOPHAGEAL REFLUX DISEASE Authors: Ch. B. Praveena Devi , B. KOUSHIK, M. RAJYALAXMI, R. SONY, K. GAYATRI, VSS GUPTA ATYAM AND B. MAHESHWARI
ABSTRACT
The symptoms of sub sternal burning and/or acid regurgitation brought on by the abnormal reflux
of stomach contents into the esophagus are what define gastroesophageal reflux (GERD). Most
patients with chronic heartburn will report having trouble falling asleep or staying asleep through
the night due to reflux symptoms. Reflux symptoms are becoming more and more common in the
developed world.
The effectiveness of both LNF and CNF over ten years was found to be similar regarding the
alleviation of GERD symptoms, the use of proton pump inhibitors (PPIs), quality of life
improvements, and objective reflux control as demonstrated by impedance studies. Consequently,
the long-term findings from this trial provide level 1 evidence supporting LNF as the preferred
surgical option for GERD
Keywords: gastroesophageal reflux (GERD), Reflux symptoms, developed world Publication date: 01/04/2026 https://www.ijbpas.com/pdf/2026/April/MS_IJBPAS_2026_10060.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2026/15.4.10060