ABSTRACT

Background: Corticosteroids are powerful anti-inflammatory drugs that have been used to treat a variety of diseases for over seven decades, the administration of corticosteroids may have possible hazards, ranging from minor adverse medication reactions to more serious considerations, among the more serious side effects noted with systemic corticosteroid therapy, particularly when used at high doses for prolonged periods. Therefore, educational interventions among healthcare professionals and patients are required to enhance rational drug use Objective: To assess the safety and efficacy of long term and short-term use of corticosteroids Materials and methods: The Cross-sectional study was conducted in the Mallige Medical Centre and included a total case of 539 in which patients receiving corticosteroids during the study period of six months. The study data was collected through the pretested and validated questionnaires that included the demographic details, past medical history, past medication history, presenting complaints, corticosteroid duration etc. Results: In a total of 539 patients with prescribed corticosteroids for In-patient and Out-patient, 205 (38%) were male and 334 (62%) were female. The study findings concluded that Short Term Corticosteroid use is most widely prescribed, 487 (90.4%) and efficient than of long-term Corticosteroid therapy, 52 (9.6%). 298(55%) patients were found to have drug interaction. Themajority non-corticosteroid drugs interacting with corticosteroid were Pantoprazole 174 (32.3%) followed by Fosaprepitant 17 (3.2%). Conclusion: The study findings concluded that Short Term Corticosteroid use is most widely prescribed about 487(90.4%) and efficient than of long-term Corticosteroid therapy 52 (9.6%) out of 539 patients in the study population. Keywords: Corticosteroids, glucocorticoids, mineralocorticoids, ADR, drug interaction, HPA- axis, short-term and long-term duration
Publication date: 01/04/2026

https://www.ijbpas.com/pdf/2026/April/MS_IJBPAS_2026_10072.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.4.10072