ABSTRACT

The present study seeks to develop herbal toothpaste from neem and karanj twigs. The plant extract constituents have antimicrobial, anti-inflammatory, and anti-caries properties, which are useful in the prevention of bad odors through dental hygiene. Three formulations of herbal toothpaste were prepared by using Pongamia pinnata twig powder and Azadirachta indica twig extract. All the prepared toothpaste formulations (TF1, TF2, TF3) and marketed formulations (MF1, MF2) were evaluated for pH, extrudability, spreadability, foamability, homogeneity, cleaning action, and antibacterial activity, with comparisons to marketed formulations. Herbal toothpaste preparations satisfy all of the requirements for maintaining the mouth fresh and preventing the bacteria that cause tooth decay. The antimicrobial study against E. coli (Escherichia coli) shows that prepared herbal toothpaste has significant antibacterial action. The results showed that the herbal toothpaste performed comparably or better in terms of antibacterial activity and cleansing effect of marketed formulations. The Research results indicate that such herbal toothpaste may represent a beneficial, environmentally friendly alternate to currently available synthetic oral care products. Keywords: Toothpaste, herbal, antibacterial activity, pH, tooth decay, oral care product, cleansing activity
Publication date: 01/04/2026

https://www.ijbpas.com/pdf/2026/April/MS_IJBPAS_2026_10114.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.4.10114