ABSTRACT

Introduction: Syphilis, caused by Treponema pallidum, is a significant global health issue with over one million daily cases and six million new cases diagnosed annually. It is a chronic illness with potential co-infections with HIV and hepatitis. Serological screening is crucial to prevent transfusion-transmitted illnesses. Although syphilis prevalence and clinical patterns are improving in India, it remains a serious public health issue with regional differences. Aim: To find out how common syphilis is among the patients at Civil Hospital, Shillong. A retrospective study. Materials and Methods: All of the syphilis cases that were reported to the Laboratory Medicine department at Civil Hospital Shillong between January 1, 2019 and December 31, 2022. Based on clinical or Serological evidence, syphilis was identified. Statistical analysis was performed using R-software to assess the data. The significance value was set at 0.05, and any result that was less than or equal to 0.05 was considered statistically significant. Result: 645 samples in all were examined during the investigation. Total syphilis antibody sero-prevalence was 47 (7.25%) between 2019 and 2022. Conclusion: The recent study demonstrated that syphilis seroprevalence among persons in thisarea is constant, but it is still encouraged that people get tested for the disease since it is recoverable and will help to lessen the symptoms of tertiary syphilis that cannot be treated. Keywords: Syphilis, Treponema pallidum, Sexually Transmitted Infections, Seroprevalence, RPR
Publication date: 01/05/2026

https://www.ijbpas.com/pdf/2026/May/MS_IJBPAS_2026_9340.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.5.9340