EFFECTIVENESS OF TOCOLYTICS IN PRETERM LABOUR: A CLINICAL ANALYSIS OF CONTRIBUTING FACTORS Authors: V Sireesha , N. CHAITANYA, MEGHANA. CH, K. MEGANA, C. VANI AND T. RAMARAO
ABSTRACT
Background: Preterm labor is one of the leading causes of perinatal morbidity and mortality. The aim
of the study is to identify the associated risk factors, to evaluate the efficacy of tocolytics in preterm
labor and also to assess the neonatal mortality and morbidity in preterm labor.
Methodology: A prospective observational study was conducted in the in-patient department of
Gynaecology and obstetrics at Gandhi Hospital over a 6 months of study period i.e., July 2023 to
December 2023 and as per the inclusion criteria 104 Preterm cases were enrolled in the study and
analyzed.
Results and discussion: The Chi-Square test is a statistical procedure for determining the difference
between observed and expected data. This test is used in our studies to corrrelate with our data. Chi-
square analysis is done between tocolytics and APGAR score at 1min and 5min; steroids and APGAR
score at 1min and 5min.The obtained p-value is <.001 with fisher exact test value of 47.467. It indicates
that there is statistically significant association between use of tocolytics and APGAR Score at 1 min,
suggesting that the administration of tocolytics might impact the Apgar scores of newborns taken at 1
min and 5min.
Conclusion:This study suggests that Preterm births cannot be prevented completely but their incidence can be
minimised by using tocolytics. Co-administration of Tocolytics and Corticosteroids will promote the
fetal outcomes and decreases the neonatal morbidity and mortality. Prediction and prevention of Preterm
labour is not possible despite of extensive research done on the subject.
Keywords: APGAR score, Cervical cerclage, Preterm labor, steroids, Tocolytics Publication date: 01/05/2026 https://www.ijbpas.com/pdf/2026/May/MS_IJBPAS_2026_10100.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2026/15.5.10100