EFFECTIVENESS OF TOCOLYTICS IN PRETERM LABOUR: A CLINICAL ANALYSIS OF CONTRIBUTING FACTORS
Authors: V Sireesha , N. CHAITANYA, MEGHANA. CH, K. MEGANA, C. VANI AND T. RAMARAO

ABSTRACT
Background: Preterm labor is one of the leading causes of perinatal morbidity and mortality. The aim of the study is to identify the associated risk factors, to evaluate the efficacy of tocolytics in preterm labor and also to assess the neonatal mortality and morbidity in preterm labor. Methodology: A prospective observational study was conducted in the in-patient department of Gynaecology and obstetrics at Gandhi Hospital over a 6 months of study period i.e., July 2023 to December 2023 and as per the inclusion criteria 104 Preterm cases were enrolled in the study and analyzed. Results and discussion: The Chi-Square test is a statistical procedure for determining the difference between observed and expected data. This test is used in our studies to corrrelate with our data. Chi- square analysis is done between tocolytics and APGAR score at 1min and 5min; steroids and APGAR score at 1min and 5min.The obtained p-value is <.001 with fisher exact test value of 47.467. It indicates that there is statistically significant association between use of tocolytics and APGAR Score at 1 min, suggesting that the administration of tocolytics might impact the Apgar scores of newborns taken at 1 min and 5min. Conclusion:This study suggests that Preterm births cannot be prevented completely but their incidence can be minimised by using tocolytics. Co-administration of Tocolytics and Corticosteroids will promote the fetal outcomes and decreases the neonatal morbidity and mortality. Prediction and prevention of Preterm labour is not possible despite of extensive research done on the subject. Keywords: APGAR score, Cervical cerclage, Preterm labor, steroids, Tocolytics
Publication date: 01/05/2026
    https://www.ijbpas.com/pdf/2026/May/MS_IJBPAS_2026_10100.pdf
Download PDF
https://doi.org/10.31032/IJBPAS/2026/15.5.10100