ABSTRACT

Osteoarthritis, common in older adults, leads to pain and disability due to cartilage breakdown and reduced synovial fluid. In Ayurveda, Sandhivata is attributed to aggravated Vata and reduced Shleshaka Kapha, causing joint degeneration and symptoms like pain, swelling, and stiffness. Rasayana therapies, particularly Naimittika Rasayana, target specific diseases to enhance vitality. Mahayogaraja Guggulu, described in classical texts, contains 31 ingredients focusing on bone, joint, and marrow health. It possesses properties that alleviate Vata and Kapha, serving as a potent remedy in managing Sandhigatavata. Mahayogaraja guggulu does Vata Shamaka and Kaphavatahara properties. MahaYogaraja is a powerful anti-oxidant, and stimulates the immune system's white blood cells (WBC’s). (Guggulu's lekhana effect eliminates the Aamatva accumulated in the joints and additionally the alchoholic extracts ofGuggulu also exhibits anti-oxidant property. The compound’s antioxidant properties are attributed to prevent oxidative stress and cartilage destruction. This review focuses on antioxidant and Rasayana effect of Mahayogaraja Guggulu in Janu Sandhigata Vata. Keywords: Mahayogaraja guggulu, Rasayana, Janu sandhigata vata, Antioxidant
Publication date: 01/05/2026

https://www.ijbpas.com/pdf/2026/May/MS_IJBPAS_2026_10138.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.5.10138