ABSTRACT

This study involved formulating five different polyherbal tablets (F1 to F5) using three standardized extracts: Momordica charantia (which contains 3% bitter principle), Cinnamomum cassia (10% total phenols), and Stevia rebaudiana. The tablets used wet granulation with microcrystalline cellulose (MCC PH101) as a diluent, Povidone K30 as a binder, and magnesium stearate and talc as glidants. To evaluate the tablets, methylparaben (0.1% to 0.2%) and propylparaben (0.1% to 0.25%) were used to create different tablet compositions (F2 to F5). The tablets were then tested for precompression parameters (angle of repose, bulk density, tapped density, and compressibility index) and post-compression parameters (weight variation test, friability test, hardness test, and stability studies). All formulations (F1 to F5) met the required specifications and were found to be stable for up to 90 days. The tablets containing propylparaben (F4&F5) were harder and less friable than those containing methylparaben (F2&F3), indicating better dissolution. The concentration of preservatives affected the tablets. Keywords: Polyherbal, Momordica, Cinnamon, Stevia, Formulations
Publication date: 01/05/2026

https://www.ijbpas.com/pdf/2026/May/MS_IJBPAS_2026_10174.pdf

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https://doi.org/10.31032/IJBPAS/2026/15.5.10174