EVALUATION OF ANTINOCICEPTIVE ACTIVITY OF HYDROALCOHOLIC EXTRACT OF WHITE JUTE SEEDS
Authors: Biswas J , MUKHERJEE M, MANNA R, ROY P*, MAJUMDAR M, ROY S, DAS S, DEY S, SAHA P, CHANDA A, BHUNIA I, DAKSHI S, SARDAR P, PRASAD MK, DATTA K AND MANNA M

ABSTRACT
Background: Analgesics are drugs that relieve pain. These drugs treat the symptoms of pain without treating its underlying cause. They usually function by either altering how the brain interprets pain or by decreasing inflammation at the location of the pain. The utilization of medicinal plants are the main components of herbal medicine. It is the oldest method of treatment, and in recent decades, research on medicinal plants and their traditional uses across the world has drawn more attention. Corchorus capsularis is one of the important medicinal herbs having wide range of pharmacological activity like antioxidant, anti-inflammatory, analgesic antipyretic, antimicrobial and numerous additional effects of pharmacological nature. Traditionally, the Corchorus capsularis has been used to treat a variety of physiological problems, including pain. Aim: The analgesic effect of Seeds of Corchorus capsularis (Jute) was estimated in this study to evaluate its traditional use. Method: The seeds of Corchorus capsularis were collected, dried and extracted with 70% hydroalcoholic extract by soxhlation method, the extract was evaporated by using Soxhlet apparatus. Using the tail flick method, the sample's ability to reduce pain wasevaluated at two distinct dosages, 250 mg/kg (CCLD) 500 mg/kg (CCHD), where paracetamol was taken as a standard drug. Conclusion: In both experimental doses Corchorus capsularis has shown significant analgesic property, though the CCHD has shown the similar action like paracetamol. Keywords: Corchorus capsularis, Hydroalcoholic extract, Paracetamol, Tail flick method
Publication date: 01/05/2026
    https://www.ijbpas.com/pdf/2026/May/MS_IJBPAS_2026_10185.pdf
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https://doi.org/10.31032/IJBPAS/2026/15.5.10185