ABSTRACT

Prescription cascades occur when adverse drug reactions (ADRs) are mistaken for new diseases, leading to the unnecessary prescription of additional medications. This cycle often results in polypharmacy, particularly among the elderly and individuals with multiple health conditions. Excessive medication use increases the risk of adverse effects, healthcare costs, and poor patient compliance, further complicating overall health management. In contrast, Ayurveda advocates a holistic and individualized approach to treatment through the principle of Shuddha Chikitsa (pure treatment). This approach focuses on precise diagnostics and patient-specific treatment protocols, ensuring that only necessary medications are prescribed. One of the key diagnostic frameworks given in Ayurveda, Dashavidha Parikshya Bhava (Ten- fold examination), provides a systematic and comprehensive approach to patient assessment, aiding in precise diagnosis, preventing inappropriate prescriptions, and minimizing the risk of cascading drug reactions. This article explores the mechanisms and risks associated with prescription cascades and polypharmacy while presenting Chikitsa Siddhanta as described by Acharya Charaka for rational prescribing. By integrating traditional wisdom with modern deprescribing strategies, this paper advocates for a patient-centered, comprehensive approach to medication management. Implementing these principles can help minimize the risks associated with overmedication, enhance treatment efficacy, and promote long-term health outcomes. Keywords: Prescription cascade, Polypharmacy, Inappropriate Prescribing, Shuddha Chikitsa, Dashvidh parikshya bhav
Publication date: 01/06/2026

https://www.ijbpas.com/pdf/2026/June/MS_IJBPAS_2026_10240.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2026/15.6.10240