ADVANCES IN IMMUNO-ONCOLOGY: PROSPECTS, CHALLENGES AND EMERGING TRENDS Authors: Mrudula Y* And Jhansi Lakshmi V
ABSTRACT
Nowadays, cancer immunotherapy is a cutting-edge malignancy treatment. Immunotherapy
has been shown to offer unmatched benefits over conventional anti-tumor therapy in several
experimental and clinical studies, which can increase both progression-free survival (PFS) and
overall survival (OS). On the other hand, immunotherapy is unclear and complex. A
hyperactive immune system might potentially result in serious side effects from
immunotherapy. Immunological checkpoints that are more efficient and have fewer side effects
are constantly being investigated. By weighing the benefits and drawbacks of immunotherapy
and closely monitoring its future development trend, this review provides an overview of
current advancements in the field. It suggests a new approach to tumor treatment. In terms of
survival rates and overall quality of life, cancer immunotherapy has led to substantial
advancements in patient outcomes compared to traditional treatments like chemotherapy,
radiation, and surgery. It has become a key component of modern cancer care, with applications
ranging from early-stage (adjuvant and neo adjuvant) settings to advanced metastatic disease
across various cancer types.
Keywords: Cancer immunotherapy, Immune checkpoint blockade therapies, natural
killer (NK) cells, ACI (adoptive cellular Immunotherapy) TGR (tumor growth rate) Publication date: 01/06/2026 https://www.ijbpas.com/pdf/2026/June/MS_IJBPAS_2026_10259.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2026/15.6.10259