ABSTRACT

Dried blood spot (DBS) technology has emerged as a useful instrument for qualitative and quantitative biological examination in recent years. Once the sample has dried, analysis can be done using contemporary analytical, immunological, or genomic techniques. DBS has been referred to as the best technique for biomaterial sampling because of certain inherent benefits, such as the low amounts of biomaterials needed, the lack of special storage and transportation conditions for samples, the enhanced stability of analytes, and the decreased risk of infection from contaminated samples. Since the 1960s, Blood that has been spotted and dried on a matrix has been examined in clinical chemistry. often known as "dried blood spot" or DBS, mostly for newborn screening. Numerous clinical analytes, such as lipids, small molecules, and nucleic acids, have since been effectively measured with DBS. Despite being an intriguing substitute for traditional venous blood collection, this pre analytical method is not widely used. Here, we examine how DBS technology is used in clinical chemistry. Keywords: Dried blood spots (DBS); new born screening (NBS); polymerase chain reaction (PCR); enzyme-linked immunosorbent assay (ELISA) Received 24
Publication date: 01/07/2026

https://www.ijbpas.com/pdf/2026/July/MS_IJBPAS_2026_10349.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2026/15.7.10349