ABSTRACT

Background: Dyslipidaemia, a major cardiovascular risk factor, involves abnormal lipid profiles including elevated LDL-C, triglycerides, and reduced HDL-C. Emerging evidence links sleep disturbances to metabolic dysregulation, yet associations with specific sleep disorders remain underexplored. Methods: This narrative review synthesises evidence from five open-access observational studies (PubMed Central, up to January 2025) on sleep characteristics (duration, quality, catch-up sleep, night-shift work, OSA, insomnia) and dyslipidaemia in adults. Studies were selected using Boolean searches (e.g., "Sleep AND Dyslipidaemia"), with qualitative synthesis across domains like circadian disruption and gender effects. Results: Weekend catch-up sleep showed inverse dyslipidaemia associations inoptimal sleepers; night-shift work heightened risks via circadian misalignment. Severe OSA linked to hypercholesterolaemia and low HDL-C primarily in males, potentially moderated by oestrogen. Poor sleep quality correlated with adverse lipids in diabetics; insomnia lacked direct ties except elevated LDL-C in hypnotic users. Conclusions: Sleep duration, OSA, and shift work emerge as heterogeneous dyslipidaemia correlates with sex-specific effects. Longitudinal studies are needed for causality and prevention. Keywords: circadian disruption; dyslipidaemia; insomnia; obstructive sleep apnoea; sleep duration
Publication date: 2026/10/01

https://www.ijbpas.com/pdf/2026/October/MS_IJBPAS_2026_10498.pdf

Download PDF
doi.org/10.31032/IJBPAS/2026/15.10.10498