A REVIEW ON PATHOPHYSIOLOGICAL UNDERSTANDING OF MAJJAVAHA SROTA DUSHTI AND ITS CORRELATION TO THE AVASCULAR NECROSIS Authors: Dwivedi A , PAUL SD AND JAIN AK*
ABSTRACT
Majjavaha Srotas falls under the category of Abhyantara Srotas and Mula Sthana (root or
primary site) of Majjavaha Srotas is suggested to be Asthi (bone) and Sandhi (joints). In the context
of Ashtanga Samgrahakara, Parva and Asthi are classified as the Mula Sthana of Majjavaha
Srotas. The pathological changes associated with Majjavaha Srotas Dushti can be correlated to
the avascular necrosis (AVN), which also possesses symptomatic similarity to Asthimajjagata
Vata. Bone marrow degeneration is an early and significant aspect of the pathologic process
associated with AVN and its development and progression. Bone marrow degeneration is
attributed to disruption of blood supply to the affected bone which also triggers pathogenesis of
Avascular Necrosis (AVN). Pathophysiologically, AVN occurs due to insufficient blood flow
resulting from the occlusion of the bone’s vascular supply, due to trauma, embolism, thrombosisor idiopathic causes; contributing to Srotorodha resulting in ischemic necrosis. The symptoms may
include bone pain, restrictions in joints, weakness, insomnia and numbness, etc. Vitiation can
occur from poor diet, ageing, lifestyle factors, trauma, stress and chronic disease, etc. This review
study observed that the bone marrow degeneration caused by disrupted blood supply is the key
pathological event linking Majjavaha Srotas Dushti with Avascular Necrosis.
Keywords: Majjavaha Strota, Avascular Necrosis, Asthimajjagata Vata, Srotorodha Publication date: 2026/10/01 https://www.ijbpas.com/pdf/2026/October/MS_IJBPAS_2026_10528.pdfDownload PDFdoi.org/10.31032/IJBPAS/2026/15.10.10528