Introduction: Ahiputana, clinically correlated with diaper dermatitis, is a common inflammatory skin
condition in infants caused by prolonged exposure to moisture, urine, and faeces. In Ayurveda, it is
described under Kshudra Rogas, primarily involving vitiation of Kapha, Pitta, and Rakta, leading to
symptoms such as erythema, itching, discharge, and lesions. The prevalence ranges from 4% to 35% in
early childhood. Conventional topical therapies provide symptomatic relief but may be associated with
adverse effects on prolonged use. Arjunadi Lepa, possessing anti-inflammatory and wound-healing
properties, is explored in a modified cream form to enhance therapeutic efficacy and acceptability.
Methods: A randomized, open-label, parallel-group clinical trial will be conducted on 120 infants
diagnosed with Ahiputana. Participants will be randomly allocated into two groups (n=60 each). Group
A will receive Panchavalkala ointment, and Group B will receive Arjunadi cream, applied locally thrice
daily for 7 days. Primary outcomes will be assessed using the Diaper Dermatitis Severity Scale, while
secondary outcomes include the FLACC scale for pain and ItchyQuant scale for itching, evaluated on
Day 0, 8 and 15. Expected Outcomes: The study is expected to demonstrate significant improvement
in both groups, with Arjunadi cream showing enhanced efficacy in reducing erythema, itching,
discharge, and lesions. Improved patient compliance and faster healing response are anticipated.Conclusion: This study aims to establish Arjunadi cream as a safe, effective, and child-friendly
alternative in the management of Ahiputana, contributing to evidence-based Ayurvedic practice.
Keywords: Ahiputana, Diaper Dermatitis, Arjunadi Cream, Panchavalkala Ointment, Ayurveda, Randomized Controlled Trial
Publication date: 01/11/2026
https://www.ijbpas.com/pdf/2026/November/MS_IJBPAS_2026_10583.pdf
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https://doi.org/10.31032/IJBPAS/2026/15.11.10583
