Background: Hypothyroidism is a relatively common condition in which the thyroid gland
fails to produce sufficient hormones. These hormones are significant because they assist in
controlling factors such as energy levels, metabolism, and body temperature. Objective: To
evaluate the diagnostic approaches, treatment strategies, and guideline adherence in the
management of hypothyroidism among hospitalized patients. Methods: An ambi-directional
observational study was conducted on 251 adult inpatients diagnosed with hypothyroidism.
Data were collected using a structured questionnaire, including demographic details, clinical
presentation, comorbidities, thyroid profile, class of hypothyroidism, imaging, treatment
regimen (with levothyroxine), Billewicz scoring, and follow-up monitoring. Inclusion and
exclusion criteria were strictly followed to ensure relevance and accuracy. Results: Out of 251
patients, 80.9% were female, with the majority (55.8%) aged between 50–69 years. Primary
hypothyroidism was the most common class (91%), and 91.26% of patients showed elevated TSH
and low T4 levels. Common symptoms included constipation, dry skin, and weight gain, as assessed
by Billewicz scoring. The most frequently prescribed current levothyroxine doses were 75 mcg and
50 mcg (each in 27.5% of patients). While 31.9% were newly diagnosed, others had prior treatment,
with 25 mcg being the most common past dose. A majority (70.91%) were treated according to
ATA guidelines. Co-morbidities included hypertension (38.1%) and type 2 diabetes (28.13%).
Conclusion: The study highlights a strong female predominance and midlife onset inhypothyroidism. Rational prescribing patterns were observed, with appropriate levothyroxine
dose titration based on hormonal levels and clinical symptoms. High adherence to ATA
guidelines indicates evidence-based practice.
Keywords: Hypothyroidism, Subclinical hypothyroidism, Levothyroxine, Thyroid
profile, TSH monitoring
Publication date: 01/11/2026
https://www.ijbpas.com/pdf/2026/November/MS_IJBPAS_2026_10587.pdf
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https://doi.org/10.31032/IJBPAS/2026/15.11.10587
